How awesome is this? A company called Kinetic Communications has created a mod for Rock Band so that people in wheelchairs can play.
Previously, the wheelchair-bound couldn't rock out because the game's kickpedal couldn't be disabled, but Kinetic's hack, which was created for one of their disabled clients who wanted to play, allows you to unplug it and bypass the kickpedal function.
For under $20, all you need to buy is a few supplies, and the directions sound achingly simple. Nice work, Kinetic!